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BIOENGINEER.ORG - Bioengineering
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Immune Cells Caught arming the Deadliest Breast Cancer to Spread
1+ day, 10+ hour ago (53+ words) Triple-negative breast cancer is the form of the disease that clinicians fear most. Lacking the three molecular targets — the estrogen receptor, the progesterone receptor and the HER2 protein — that anchor modern targeted therapies, it leaves patients with fewer options and a…...
Lab Models Take Center Stage in the Race to Improve Cancer Immunotherapy
1+ day, 12+ hour ago (583+ words) Cancer immunotherapy has transformed the treatment landscape for many patients with solid tumors, delivering durable responses in diseases that once resisted nearly every therapeutic approach....
Lipid Metabolism Emerges as a Central Driver of Drug Resistance in
1+ day, 15+ hour ago (71+ words) Aggressive non-Hodgkin lymphoma remains one of the most stubborn challenges in modern hematology. Even with a therapeutic arsenal that now includes rituximab-based immunochemotherapy, targeted kinase inhibitors, immune checkpoint blockade, and chimeric antigen receptor T-cell therapies, a substantial fraction of patients…...
Radiation or Surgery After Dual Immunotherapy Fails to Extend Survival in
1+ day, 17+ hour ago (574+ words) One of the most persistent questions in modern lung cancer care has just received a sobering answer....
Cancer Myths Run Rampant in Central Uganda, Survey of 428 Adults Finds
1+ day, 20+ hour ago (753+ words) A sweeping community survey in central Uganda has revealed that public awareness of the mythical causes of cancer is strikingly low, with residents endorsing a wide range of unproven exposures as genuine carcinogens while failing to recognise them as myths....
Ruxolitinib Shows Stronger Response in Primary Than Secondary HLH,
1+ day, 22+ hour ago (632+ words) Hemophagocytic lymphohistiocytosis is one of the most feared syndromes in medicine, a runaway immune firestorm in which the body’s own scavenger cells turn against blood cells and organs, and it can kill within weeks if untreated....
AI-enabled clinical trials
2+ day, 10+ hour ago (1349+ words) {“title”:”AI-Enabled Clinical Trials Are Poised to Transform How New Medicines Are Tested”,”html”:”Clinical trials have long been the slowest, most expensive and most unpredictable stage of medical research. A promising molecule identified in the laboratory can take a…...
NIH awards $3.3 million to Upstate for new leukemia immunotherapy research
3+ day, 15+ hour ago (779+ words) The immune system’s ability to hunt down and destroy cancer cells depends on a delicate molecular recognition process, one that acute myeloid leukemia has become disturbingly good at evading....
Keratin 17 promotes endometrial cancer aggressiveness through
3+ day, 21+ hour ago (88+ words) Endometrial cancer, one of the most common gynecological malignancies worldwide, has been quietly rising in incidence for decades, and for patients whose disease advances or recurs, the therapeutic landscape remains frustratingly thin. Now, a team of researchers at The First…...
Hierarchical AI model unifies single-cell multiomics data through deep
4+ day, 4+ hour ago (829+ words) Researchers at the Indian Institute of Technology Kanpur, working with a collaborator at the University of California, Irvine, have unveiled a new artificial intelligence framework that promises to make sense of one of the most data-rich but technically unruly corners…...